The Go/No-Go decision for Phase I isn't a formality. It's a high-stakes boardroom moment where leadership decides whether to commit millions to moving forward. They evaluate ten critical factors: scientific rationale, competitive landscape, commercial potential, regulatory pathway, manufacturing readiness, financial capacity, organisational capability, partnership strategy, risk tolerance, and strategic fit.

When you understand what's at stake in this decision, you'll never again see Phase I as "just a small pilot study." You'll recognise it for what it truly is: a major strategic commitment that can define careers, validate acquisitions, and determine whether a company survives or thrives.